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ECM control of the micro-ecology of the experimental study

Test method for detecting sub-pharyngeal 542, from 131 throat isolates of group A Neisseria meningitidis strain growth inhibition, inhibition rate was 24.17%. Inhibitory rate of general healthy 25.53%, flow tracing close contacts of patients was 22.37%. Meningitis patients is 0,[link widoczny dla zalogowanych], the statistical test was no significant difference between the three (xz = 3.85P> 0.05). Table 1 when the pharyngeal group A group of normal seedlings {} 4 Nm fraud charges inhibition by 2,2 A Neisseria meningitis group outfitting the growth of normal human pharyngeal meningococcal B strains of microorganisms in the pro sergenti 7 Inhibition of pathogenic bacteria isolated from the inhibition of the Neisseria meningitidis group A growth-positive strains, 41 strains were detected on the selected group B Neisseria meningitidis microorganisms in the growth inhibition, resulting in 23 pairs of B Neisseria meningitis group of students described the first six Qiao Qian Zhang Jun: meningitis prevention and control of the micro-ecology of the experimental study 355 long inhibited, accounting for 5610 percent; inhibited the growth of alpha hemolytic streptococcus strain for 23 ; another 21 strains could inhibit the growth of beta hemolytic streptococcus, accounting for 51.22%: 19 inhibited the growth of Corynebacterium diphtheriae. Accounted for 46.34%; lO bacteria strains could inhibit the growth of one hundred marks,[link widoczny dla zalogowanych], accounting for 24.39%; I9 strains could inhibit the growth of Streptococcus pneumoniae, accounting for 46.34%; 18 can inhibit the growth of Staphylococcus aureus, accounting for 43. 90%. 5 to 8 experimental strains standard strains were tested inhibited the growth. Pharyngeal bacterial flora of 23 normal metabolites A, B Neisseria meningitidis inhibition of our elected eight pairs of A, B Neisseria meningitis group aiming inhibition of growth were highly strain detected antibacterial metabolites, the result 8 strains of metabolites A, B Neisseria meningitidis were tested growth inhibition. 3 discussion for many years, most people committed to the prevention of disease-specific mechanism, and less attention to non-specific protection, but there is no ideal number of diseases specific measures, and the new genus, species, type of pathogen is constantly emerge. Micro-ecology that the normal flora in the host organism and the surface of each cavity to form a specific biological barriers, external attack of pathogenic micro-organisms from the antagonist with 【cited. Feng experiments show that the existence of human pharyngeal group A inhibited the growth of Neisseria meningitidis normal flora in the investigation 』, base rate of 24.17% inhibition positive. And generally healthy, epidemic cerebrospinal meningitis epidemic cerebrospinal meningitis patients and close contacts of patients positive rate of inhibition between the three groups was not significant. A group on the inhibition of growth of Neisseria meningitidis strains positive for the further study shows that 56.10% of group B Neisseria meningitidis inhibit longevity, the other for alpha-hemolytic streptococcus,[link widoczny dla zalogowanych], beta-hemolytic chain cocci, Corynebacterium diphtheria,[link widoczny dla zalogowanych], one hundred cough bacteria, Streptococcus pneumoniae, Staphylococcus aureus was inhibited positive strains accounted for 56.10%, 51.22%, 46.34%, 24.39%, 46.34% , 43.90%. 5 to 8 experimental strains standard strains were tested inhibited the growth, indicating that the normal human throat flora bacteria antagonistic effect on the multiplicity and non-specific. Normal flora of bacteria antagonistic mechanism of inhibition of pathogenic bacteria, mainly parasitic part of the occupation, interference bacteria attached to compete for nutrients and antibiotic 【cited. Feng experiments showed that some of the normal flora of bacteria in the growth process can really produce a substance can inhibit the A, B Neisseria meningitidis growth. Further research on the experimental results show that people with normal pharyngeal flora and other non-specific way to prevent meningitis and other immune diseases, in particular, there is no ideal vaccine diseases, and emerging new diseases. Is of great significance.

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