polo outlet online Such as injection of 5FU by end

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Injection of 5FU such as the treatment by endoscopy term efficacy of esophageal and cardiac carcinoma

Endoscopy can be discussed into the soft diet treatment of local injection of tumor digest was carried out in recent years one of the new technologies, domestic rarely reported. Down by 25 late in the esophagus and cardia local injection of the initial expense of drug treatment beds observations, we believe that t (1) local drug injection, there is certainly short-term effect, with a safety barrier, effective, side effects, easy to accept such patients advantages. (2) injection of local tumor response and dose and concentration. When 5FU concentration of lOmg / ml each lOOmg, hormone concentration 0.33mg/ml basket pull out each crack 2mg, alone or no injection at the same time points ulcers, alone or in combination with mitomycin concentration of 0.5mg / ml, dose 2 ~ 4rag, 5F. U concentration of 15mg/ml dose of 150mg, local injection therapy with different degrees of more ulcers stopped Mi 56 - Castle Ridge mandarin duck,[link widoczny dla zalogowanych]! Plastic 璺 board. 1 plastic Progress parvovirus Cancer Research Institute of Digestive Disease, Shanghai, Shanghai Ruijin Hospital, Second University Union WU Yun-lin Guo Xiaojun Wang Hao Yu wind Qi Shu-Dong Xiao Jiang Shaoji review over the trial of certain viruses (including DNA viruses and viral reverse transcription of RNA ) the carcinogenic effects of experimental and clinical research has confirmed that it has recently been discovered,[link widoczny dla zalogowanych], one of the parvovirus Yun (parvoviruse0, PV) in certain viruses (such as parvovirus H-l, and adeno-associated virus, etc.) has significant anti-tumor effect. Parvovirus cancer, fully observe the characteristics of parvovirus cancer, efforts to explore the possibility of its clinical application. This article briefly describes some of the research status and progress. Characteristics and origin of parvovirus parvovirus is one of the smallest known animal viruses with diameters of about 18 ~ 25mm. Parvovirus coat protein is composed of only a few polypeptide chains of 2O face, said body, the genome consists of a five thousand or so nucleotides of single-stranded linear DNA molecules, containing only a few viral structural protein genes (1 ), parvovirus replication cycle, including: absorption in the host cell surface receptors, penetrate the cell membrane, the nuclear migration of shelling in the nucleus,[link widoczny dla zalogowanych], extending DNA3 side and self 【matter of a chain of virus DNA (V-chain) as the template synthesis But two weeks after the erosion message after each loss, ulcer healing, reduced lesions, obstructive symptoms lifted. MMC at high concentrations, high dose prone to ulcers, but the elimination of tumor, better relief of obstruction. Alternate use of drugs and combined with better than that with a drug. <3) when this group of patients the first injection of more than a chest sting, 1O ~ 2O minutes the symptoms have disappeared. Mitomycin concentration in 0.5rag/ml, a dosage of 4mg more obvious when the local irritation, being an individual patient can not eat for 6 hours and relieve itself make a chain (c chain) to form double-stranded copy of the form, c-chain base Western express and Taiwan into the viral structural protein, the c-chain as a template into a sub-viral DN table after soil reaches a certain amount of virus particles, the cell lysis, the child virus release (1,4). Because parvovirus genome is extremely simple and therefore almost entirely dependent on viral replication in the host cell enzyme. According to the need for viral replication with the help of other viruses, mammals can be divided into autonomous parvovirus and parvovirus dependent two categories, the former can be independent of host cells to complete its replication process; the latter mainly refers to the adeno-associated virus (AdenoassoclatevirusAAV) , depend not only on host cell proliferation, but also Lou animal feeding many different types of parvovirus, the current research focuses on cancer hamster osteolytic viruses H-l, mouse minute virus (MVM) and adeno-associated virus (AAV), etc. (5). Parvovirus from tumor tissue, tumor cell lines, tumor virus, or carcinogen-treated animals were isolated and normal tissues, so people initially suspected as the cause of the tumor, but it quickly jumped to study the false negative results , Parvovirus not only does not induce tumors, while the head was significant anti-tumor effect). Large number of experimental studies have confirmed parvovirus infection can significantly reduce spontaneous tumor in addition In addition, the role has not been clear cut, such as nausea, general malaise, leukopenia, liver damage and so on. Our local injection therapy by endoscopy of upper digestive tract cancer, asked shorter. Cases the accumulation of small, look at the recent observation, the lesions reduced, the lifting of esophageal stricture, improve the consumption of short-term effect is positive. Therefore, we believe that the tigers in the late stage inoperable patients with therapeutic value, while if A systemic treatment with Western medicine, is conducive to the consolidation effect

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