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A small study conducted by researchers at Duke University Medical Center and the University of Texas M.D. Anderson Cancer Center found a vaccine to conventional brain cancer therapy extended the life of people with glioblastoma .
The vaccine's apparent ability to stimulate an immune system response indicates a possible link to prolonged survival in GBM patients. However co-lead researcher Dr. Amy Heimberger from M.D. Anderson cautions that the numbers are too small to make a definitive conclusion about the usefulness of the vaccine.
National Cancer Institute. "Brain Tumor" (accessed October 7, 2010).
Study Finds Brain Cancer Vaccine May Prolong Life
The case-controlled study published online in October 2010 in the Journal of Clinical Oncology involved 35 patients recently diagnosed with GBM. All of the study participants received surgery, radiation and chemotherapy drug. Surgery and radiation are standard treatments for GBM. Chemotherapy is generally not regarded as curative for GMB but it may modestly prolong survival, notes the University of California coach wedge grey, San Francisco.
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Business Week. "Vaccine Studied for Deadly Brain Cancer" (accessed October 7, 2010).
American Brain Tumor Association. "GBM and Anaplastic Astrocytyomas" (accessed October 7, 2010).
Less than 1 in 50 GBM patients survive 5 years or longer coach diaper bags outlet, according to the University of California, San Francisco. Patients typically live on average only 14 months after diagnosis. Gilboblastomas strike men more often than women and are most frequently diagnosed in the 45 to 55 age group. Nearly 10% of brain tumors in children are glibolastomas.
University of California, San Francisco. "Genetic Risk for Brain Cancer" (accessed October 7 Coach Satchel, 2010).
Approximately half of the patients in the study were also given regular injections of the vaccine. On average the patients who receive the vaccine survived 26 months whiles those who only underwent conventional therapy lived 15 months following the GMB diagnosis.
Brain Cancer Vaccine Outlook
CBS News. "Brain Cancer Vaccine May Extend Patients' Lives" (accessed October 7, 2010).
Brain tumors cannot be prevented but the new vaccine seems to shut down a growth factor linked with GBM. Approximately one-third of all glioblastomas are provoked by a highly aggressive cancer gene, described by Duke University professor of neurosurgery Dr. John Sampson as the “worst of the worst.”
Brain Cancer Vaccine Won’t Prevent GBM
The National Cancer Institute says approximately 13,000 people in the U.S. will die of brain and other nervous system malignancies in 2010. The statistics are especially bleak for a type of brain cancer called glioblastoma or GBM. GBM claimed the life of U.S. Senator Ted Kennedy in 2009. Any tumor that arises from the supportive tissue of the brain or glial is called a glioma. Approximately 50% of giloma tumors are glioblastomas, according to the American Brain Tumor Association or ABTA.