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Clinical features, diagnosis, treatment and prognosis of multiple primary colorectal carcinoma
inpredictingmetachronousmultiplecolorectalcarcinomasaftersurgery:acohort—likestudy.DisColonRectum2002;45:329—333MasubuchiS,KonishiF,TogashiK,OkamotoT,SenbaS,ShitohKKashiwagiHKanazawaKTsukamotoTThesig—nificanceofmicrosatelliteinstabilityinpredictingthedevelop—mentofmetachronousmultiplecolorectalcarcinomasinpa—tientswithnonfamilialcolorectalcarcinoma.Cancer1999;85:1917—192421HoriiA,HanHJ,ShimadaMYanagisawaAKatoYOhtaH2223YasuiW,TaharaE,NakamuraY.Frequentreplicationerrorsatmicrosatellitelociintumorsofpatientswithmultipleprimarycancers.CancerRes1994,ghd hair;54:3373—3375ThibodeauSN,BrenG,SchaidD.Microsatelliteinstabilityincanceroftheproximalcolon.Science1993;260:816—819IonovY,PeinadoMA,MalkhosvanS,ShibataD,PeruchoM.Ubiquitoussomaticmutationsinsimplerepeatedsequencesrevealanewmechanismforcoloniccarcinogenesis.Nature1993,polo outlet online;363:558—56124ChenF,StuartM.Colonoscopicfollow—upofcolorectalcarcinoma.DisColonRectum1994;37:568—57225TogashiKKonishiFOzawaASatoTShitoKKashiwagiHOkadaM,NagaiH.Predictivefactorsfordetectingcolorectalcarcinomasinsurveillancecolonoscopyaftercolorectalcancersurgery.DisColonRectum2000;43(10Supp1):S47—5326EassonAM,CotterchioM,ray ban sunglasses,CrosbyJA,SutherlandH,DaleD,AronsonM,HolowatyE,GallingerS.Apopulation-basedstudyoftheextentofsurgicalresectionofpotentiallycurablecoloncancer.AnnS“r20ncof2002;9:380—38727KaibaraN,KogaS,ghd hair,JinnaiD.SynchronousandmetachronousmalignanciesofthecolonandrectuminJapanwithspecialreferencetoacoexistingearlycancer.Cancer1984;54:1870.1874EditedbyWangXLProofreadbyChenWWandXuFM
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